Arsenic, cadmium, lead and mercury levels in blood of Finnish adults and their relation to diet, lifestyle habits and sociodemographic variables
File(s)
Accepted version
Author(s)
Type
Journal Article
Abstract
The Northern Finland Birth Cohort program (NFBC) is the epidemiological and longitudinal prospective general population research program, which was established to promote health and wellbeing of the population in northern Finland. The aim of present study, as a part of the NFBC program, was to analyze the blood levels of arsenic (B-As), cadmium (B-Cd), lead (B-Pb), total mercury (B-Hg) and selenium (B-Se); to compare these levels with threshold limits; to study sociodemographic factors; and to correlate these levels with calcium and haemoglobin. The study was comprised of 249 NFBC subjects, of which 123 were female and 126 were male (ages 31.1 ± 0.3 and 31.1 ± 0.4, respectively). All participants were asked to complete a questionnaire regarding diet and living habits. The geometric means (± SD) of B-As were 0.49 ± 2.80 μg/l and 0.44 ± 2.72 μg/l; B-Cd were 0.18 ± 4.02 μg/l and 0.12 ± 3.21 μg/l; B-Pb were 17.0 ± 1.8 μg/l and 9.06 ± 2.20 μg/l; B-Hg were 2.18 ± 2.02 μg/l and 1.85 ± 1.78 μg/l; and B-Se were 106.0 ± 1.3 and 94.3 ± 1.3 μg/l in males and females, respectively. Among the subjects in the present analysis, 23 % of males and 17.1 % of females had B-As levels above the ATSDR normal human levels of B-As in unexposed individuals (1.0 μg/l). The B-Pb geometric mean (12.44 μg/l) was approximately one eighth the CDC toxicological cut-off point of 100 μg/l. Twenty-one individuals (8.4 %) exceeded a B-Hg level of 5.8 μg/l. Fifty-eight females (47 %) had a B-Hg higher than 2.0 μg/l, the German Federal Environmental Agency cut-off point for women (18–69 years) who consume fish at least three times/month; therefore, their babies could be at risk of adverse effects during development.
Date Issued
2016-10-24
Date Acceptance
2016-10-03
Citation
Environmental Science and Pollution Research, 2016, 24 (2), pp.1347-1362
ISSN
1614-7499
Publisher
Springer Verlag (Germany)
Start Page
1347
End Page
1362
Journal / Book Title
Environmental Science and Pollution Research
Volume
24
Issue
2
Copyright Statement
© 2016 Springer-Verlag Berlin Heidelberg. The final publication is available at Springer via https://dx.doi.org/10.1007/s11356-016-7824-5
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000394254000025&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Subjects
Science & Technology
Life Sciences & Biomedicine
Environmental Sciences
Environmental Sciences & Ecology
Toxic metals
Metalloids
Northern Finland birth cohort 1966
NUTRITION EXAMINATION SURVEY
HUMAN EXPOSURE ASSESSMENT
HUMAN HEALTH
NATIONAL-HEALTH
FISH CONSUMPTION
REFERENCE VALUES
PREGNANT-WOMEN
METHYL MERCURY
REPRODUCTIVE-PERFORMANCE
METHYLMERCURY EXPOSURE
03 Chemical Sciences
05 Environmental Sciences
06 Biological Sciences
Publication Status
Published