Electrocorticographic Temporal Alteration Mapping: A Clinical Technique for Mapping the Motor Cortex with Movement-Related Cortical Potentials
File(s)
Published version
Author(s)
Type
Journal Article
Abstract
We propose electrocorticographic temporal alteration mapping (ETAM) for motor cortex mapping by utilizing movement-related cortical potentials (MRCPs) within the low-frequency band [0.05-3] Hz. This MRCP waveform-based temporal domain approach was compared with the state-of-the-art electrocorticographic frequency alteration mapping (EFAM), which is based on frequency spectrum dynamics. Five patients (two epilepsy cases and three tumor cases) were enrolled in the study. Each patient underwent intraoperative direct electrocortical stimulation (DECS) procedure for motor cortex localization. Moreover, the patients were required to perform simple brisk wrist extension task during awake craniotomy surgery. Cross-validation results showed that the proposed ETAM method had high sensitivity (81.8%) and specificity (94.3%) in identifying sites which exhibited positive DECS motor responses. Moreover, although the sensitivity of the ETAM and EFAM approaches was not significantly different, ETAM had greater specificity compared with EFAM (94.3 vs. 86.1%). These results indicate that for the intraoperative functional brain mapping, ETAM is a promising novel approach for motor cortex localization with the potential to reduce the need for cortical electrical stimulation.
Date Issued
2017-06-12
Date Acceptance
2017-05-23
Citation
FRONTIERS IN NEUROSCIENCE, 2017, 11
ISSN
1662-453X
Publisher
FRONTIERS MEDIA
Journal / Book Title
FRONTIERS IN NEUROSCIENCE
Volume
11
Copyright Statement
© 2017 Wu, Xie, Yao, Zhang, Sheng, Farina, Chen, Mao and Zhu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY https://creativecommons.org/licenses/by/4.0/). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000406541800001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Subjects
Science & Technology
Life Sciences & Biomedicine
Neurosciences
Neurosciences & Neurology
intraoperative
electrocorticography (ECoG)
motor cortex mapping
movement-related cortical potentials (MRCP)
VOLUNTARY MOVEMENTS
FINGER MOVEMENTS
LANGUAGE CORTEX
DESYNCHRONIZATION
OSCILLATIONS
HUMANS
AREA
EPILEPSY
IMAGERY
TASKS
1109 Neurosciences
1702 Cognitive Science
Publication Status
Published
Article Number
ARTN 326