Prediction of an estimated delivery date should take into account both the length of a previous pregnancy and the interpregnancy interval
File(s)Gestational lengths EJOG PJS BN 22.3.16(2) final.docx (78.7 KB)
Accepted version
Author(s)
Ng, KY
Steer, PJ
Type
Journal Article
Abstract
Objective
To assess the relationship between gestational lengths of the first and second pregnancies in the same women.
Study design
Observational study.
Methods
We used information from a dataset of over 500,000 pregnancies from 15 maternity units in the North West Thames, London. Data on the gestational length in days of the first pregnancy and the gestational length in days of the second pregnancy were correlated using regression models. First and second pregnancies were ascribed to the same women by identical maternal date of birth, ethnicity and maternal height (to within ±3 cm).
Results
There is a statistically significant cubic relationship between the gestational lengths of the first birth and the second birth (R 0.102, p < 0.001). The gestational length of the second pregnancy is likely to be closer to 280 days than the first pregnancy. In the 20% of women who had an interpregnancy interval of less than one year, the next pregnancy was one day shorter for every three months less than 12.
Conclusions
Although the gestation of second pregnancies exhibits regression towards the mean of 280 days, there is still a clinically important tendency for both preterm and postdates pregnancies to recur. Prediction of an estimated delivery date for second pregnancies should take into account both the length of the first pregnancy and the interpregnancy interval if it is less than 12 months.
To assess the relationship between gestational lengths of the first and second pregnancies in the same women.
Study design
Observational study.
Methods
We used information from a dataset of over 500,000 pregnancies from 15 maternity units in the North West Thames, London. Data on the gestational length in days of the first pregnancy and the gestational length in days of the second pregnancy were correlated using regression models. First and second pregnancies were ascribed to the same women by identical maternal date of birth, ethnicity and maternal height (to within ±3 cm).
Results
There is a statistically significant cubic relationship between the gestational lengths of the first birth and the second birth (R 0.102, p < 0.001). The gestational length of the second pregnancy is likely to be closer to 280 days than the first pregnancy. In the 20% of women who had an interpregnancy interval of less than one year, the next pregnancy was one day shorter for every three months less than 12.
Conclusions
Although the gestation of second pregnancies exhibits regression towards the mean of 280 days, there is still a clinically important tendency for both preterm and postdates pregnancies to recur. Prediction of an estimated delivery date for second pregnancies should take into account both the length of the first pregnancy and the interpregnancy interval if it is less than 12 months.
Date Issued
2016-04-07
Date Acceptance
2016-03-29
Citation
European Journal of Obstetrics & Gynecology and Reproductive Biology, 2016, 201, pp.101-107
ISSN
0301-2115
Publisher
Elsevier
Start Page
101
End Page
107
Journal / Book Title
European Journal of Obstetrics & Gynecology and Reproductive Biology
Volume
201
Copyright Statement
© 2016 Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/
Identifier
PII: S0301-2115(16)30143-9
Subjects
Estimated delivery date
Interpregnancy interval
Post-dates
Pregnancy length
Preterm
Repeat gestational length
Obstetrics & Reproductive Medicine
1114 Paediatrics And Reproductive Medicine
Publication Status
Published