Proposing a Parkinson's disease specific tremor scale from the MDS-UPDRS.
File(s)MovDisord2015_Rasch Tremor.pdf (180.89 KB)
Accepted version
Author(s)
Type
Journal Article
Abstract
Background: This article proposes an International
Parkinson and Movement Disorder Society (MDS)-
UPDRS tremor-based scale and describes its measurement
properties, with a view to developing an
improved scale for assessing tremor in Parkinson’s disease
(PD).
Methods: This was a cross-sectional, multicenter study
of 435 PD patients. Rasch analysis was performed on
the 11 MDS-UPDRS tremor items. Construct validity,
precision, and test-retest reliability were also analyzed.
Results: After some modifications, which included
removal of an item owing to redundancy, the obtained
MDS-UPDRS tremor scale showed moderate reliability,
unidimensionality, absence of differential item functioning,
satisfactory convergent validity with medication,
and better precision than the raw sum score. However,
the scale displayed a floor effect and a need for more
items measuring lower levels of tremor.
Conclusions: The MDS-UPDRS tremor scale provides
linear scores that can be used to assess tremor in PD in a
valid, reliable way. The scale might benefit from modifications
and studies that analyze its responsiveness
Parkinson and Movement Disorder Society (MDS)-
UPDRS tremor-based scale and describes its measurement
properties, with a view to developing an
improved scale for assessing tremor in Parkinson’s disease
(PD).
Methods: This was a cross-sectional, multicenter study
of 435 PD patients. Rasch analysis was performed on
the 11 MDS-UPDRS tremor items. Construct validity,
precision, and test-retest reliability were also analyzed.
Results: After some modifications, which included
removal of an item owing to redundancy, the obtained
MDS-UPDRS tremor scale showed moderate reliability,
unidimensionality, absence of differential item functioning,
satisfactory convergent validity with medication,
and better precision than the raw sum score. However,
the scale displayed a floor effect and a need for more
items measuring lower levels of tremor.
Conclusions: The MDS-UPDRS tremor scale provides
linear scores that can be used to assess tremor in PD in a
valid, reliable way. The scale might benefit from modifications
and studies that analyze its responsiveness
Date Issued
2015-06-11
Date Acceptance
2015-04-13
Citation
Movement Disorders, 2015, 30 (8), pp.1139-1143
ISSN
1531-8257
Publisher
Wiley
Start Page
1139
End Page
1143
Journal / Book Title
Movement Disorders
Volume
30
Issue
8
Copyright Statement
© 2015 International Parkinson and Movement Disorder Society. This is the accepted version of the following article: Forjaz, M. J. et al. (2015) Proposing a Parkinson's Disease–Specific Tremor Scale From the MDS-UPDRS. Mov. Disord.. doi: 10.1002/mds.26271, which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1002/mds.26271/abstract
Subjects
Parkinson's disease
MDS-UPDRS
tremor
Rasch analysis
Publication Status
Published