The role of small-bowel endoscopy in the diagnosis and management of small-bowel neuroendocrine tumours
File(s)jcm-13-06877.pdf (1.21 MB)
Published version
Author(s)
Bosch, Elisabet Maristany
Laskaratos, Faidon-Marios
Sodergren, Mikael
Faiz, Omar
Humphries, Adam
Type
Journal Article
Abstract
Neuroendocrine tumours (NETs) are relatively rare neoplasms but represent one of the most frequent types of primary small-bowel tumours. Their incidence is rising, and this is most likely because of their more frequent early-stage detection, physician awareness, and increasing availability and use of imaging and small-bowel endoscopic techniques, such as video capsule endoscopy and device-assisted enteroscopy, which enable the detection, localisation, and histological sampling of previously inaccessible and underdiagnosed small-bowel lesions. This review summarises the role of small-bowel endoscopy in the diagnosis and management of small-bowel NETs to assist clinicians in their practice. Small-bowel endoscopy may play a complementary role in the diagnosis of these tumours alongside other diagnostic tests, such as biomarkers, conventional radiology, and functional imaging. In addition, small-bowel enteroscopy may play a role in the preoperative setting for the identification and marking of these tumours for surgical resection and the management of rare complications, such as small-bowel variceal bleeding, in cases of portal hypertension due to the encasement of mesenteric vessels in fibrotic small-bowel NETs.
Date Issued
2024-11
Date Acceptance
2024-11-11
Citation
Journal of Clinical Medicine, 2024, 13 (22)
ISSN
2077-0383
Publisher
MDPI AG
Journal / Book Title
Journal of Clinical Medicine
Volume
13
Issue
22
Copyright Statement
© 2024 by the authors.
Licensee MDPI, Basel, Switzerland.
This article is an open access article
distributed under the terms and
conditions of the Creative Commons
Attribution (CC BY) license (https://
creativecommons.org/licenses/by/
4.0/).
Licensee MDPI, Basel, Switzerland.
This article is an open access article
distributed under the terms and
conditions of the Creative Commons
Attribution (CC BY) license (https://
creativecommons.org/licenses/by/
4.0/).
License URL
Identifier
https://www.mdpi.com/2077-0383/13/22/6877
Subjects
CAPSULE ENDOSCOPY
double-balloon enteroscopy
DOUBLE-BALLOON ENTEROSCOPY
EUROPEAN-SOCIETY
General & Internal Medicine
Life Sciences & Biomedicine
Medicine, General & Internal
RECOMMENDATIONS
Science & Technology
small-bowel neuroendocrine tumours
SURGICAL-MANAGEMENT
video capsule endoscopy
YIELD
Publication Status
Published
Article Number
6877
Date Publish Online
2024-11-15