The paper deals with the stabilization of nonlin-ear systems in which the loop is closed over a lossy non-acknowledged communication network. Given a Regional Input-to-State (ISS) stabilizing state-feedback control law, designedwithout accounting for the network-induced delays, we proposea non-acknowledged communication policy that allows to deploythe above controller over the network without any modification,while preserving the Regional ISS property. The time-varyingdelays and packet dropouts occurring on both the up-link andthe down-link are compensated through a model-based predictionscheme and a packet-management policy based on time-stamping.The consistency of the prediction, which is a major issue inthe context of nonlinear systems with an embedded networkedcontroller, is guaranteed through the exploitation of a novel move-blocking strategy for computing the command sequence to beforwarded to the actuators.