Quantitative image markers of super-resolution ultrasound
File(s)
Published version
Author(s)
Smith, Cameron
Wilson, Harvey
Yan, Jipeng
Tang, Mengxing
Type
Journal Article
Abstract
Super-resolution ultrasound, with its ability to achieve sub-diffraction resolution and directly track microvascular flow velocity in vivo, offers a level of vascular information inaccessible previously. To fully realise its clinical value, quantitative vascular markers have been explored. In this review, we explore the quantitative super-resolution markers that have been reported, with a focus on occasions where markers have been applied in a clinical or pre-clinical setting, comparing healthy and diseased cases to test the validity and usefulness of these markers. We define all the used markers from structural markers such as vessel density to velocity metrics such as flow rate, we then provide a summary showing what has been attempted and what has been found successful. We hope that this review can act as a guide both as to the range of markers that currently exist as well as indications as to what markers show potential for each clinical application.
Date Issued
2026-01-10
Date Acceptance
2025-12-20
Citation
EBioMedicine, 2026, 124 (1)
ISSN
2352-3964
Publisher
Elsevier
Journal / Book Title
EBioMedicine
Volume
124
Issue
1
Copyright Statement
© 2025 Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http:// creativecommons.org/licenses/by-nc-nd/4.0/)
Publication Status
Published
Article Number
106108
Date Publish Online
2026-01-10