HMGB2 holds the key to the senescence-associated secretory phenotype
File(s)
Published version
Author(s)
guerrero a
Gil, J
Type
Journal Article
Abstract
The
senescence
-
associated secretory phenotype (SASP) is
a
hallmark of
senescence
with
important
physiological
impact, but how it is established
is unclear
. In this issue
,
Aird and colleagues
(
2016. J Cell Biol.
xx
-
xx)
describe
how chromatin
-
bound HMGB2
fine
-
tune
s
SASP expression
by
avoid
ing
heterochromat
in
spreading
.
senescence
-
associated secretory phenotype (SASP) is
a
hallmark of
senescence
with
important
physiological
impact, but how it is established
is unclear
. In this issue
,
Aird and colleagues
(
2016. J Cell Biol.
xx
-
xx)
describe
how chromatin
-
bound HMGB2
fine
-
tune
s
SASP expression
by
avoid
ing
heterochromat
in
spreading
.
Date Issued
2016-10-31
Date Acceptance
2016-10-17
Citation
Journal of Cell Biology, 2016, 215 (3), pp.297-299
ISSN
1540-8140
Publisher
Rockefeller University Press
Start Page
297
End Page
299
Journal / Book Title
Journal of Cell Biology
Volume
215
Issue
3
Copyright Statement
© 2016 Guerrero and Gil This article is distributed under the terms of an Attribution–
Noncommercial–Share Alike–No Mirror Sites license for the first six months after the
publication date (see http ://www .rupress .org /terms). After six months it is available under a
Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license,
as described at http: //creativecommons. org /licenses /by- nc- sa /3. 0 /).
Noncommercial–Share Alike–No Mirror Sites license for the first six months after the
publication date (see http ://www .rupress .org /terms). After six months it is available under a
Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license,
as described at http: //creativecommons. org /licenses /by- nc- sa /3. 0 /).
Subjects
Developmental Biology
06 Biological Sciences
11 Medical And Health Sciences
Publication Status
Published