The influence of the industrial sector is a long-standing assumption in entrepreneurship studies, yet the mechanisms through which the industrial sector shapes entrepreneurial phenomena and the processes through which entrepreneurial actors interact with sectors to prospect, develop, and exploit entrepreneurial opportunities remain largely under-theorized and little understood. We critically reexamine the notion of “sector” in entrepreneurship research, advancing a more dynamic view of the industrial sectors captured by the concept of sector fluidity and identifying three approaches to move the sector more prominently onto the “front seat” of entrepreneurship theory and research. Defining sector-based entrepreneurial capabilities and examining their importance to advance current understanding of industry-specific determinants, processes, and outcomes of entrepreneurship, we set out an agenda for further research aimed at advancing sector studies in entrepreneurship.