Modeling type 2 diabetes GWAS candidate gene function in hESCs.
File(s)Rutter_Zeng et al_Commentary_Final.pdf (213.47 KB)
Accepted version
Author(s)
Rutter, GA
Type
Journal Article
Abstract
Type 2 diabetes is a complex polygenic disorder that affects about 1 in 12 adults. In this issue of Cell Stem Cell, Zeng et al. (2016) elegantly combine CRISPR-based gene editing in hESCs with directed β cell differentiation to investigate the functions of genes highlighted by genome-wide association studies (GWAS) for this disease.
Date Issued
2016-09-01
Date Acceptance
2016-09-01
Citation
Cell Stem Cell, 2016, 19 (3), pp.281-282
ISSN
1934-5909
Publisher
Elsevier (Cell Press)
Start Page
281
End Page
282
Journal / Book Title
Cell Stem Cell
Volume
19
Issue
3
Copyright Statement
© 2016 Elsevier Inc. All rights reserved. This manuscript is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/
Identifier
PII: S1934-5909(16)30257-0
Subjects
Science & Technology
Life Sciences & Biomedicine
Cell & Tissue Engineering
Cell Biology
GENOME-WIDE ASSOCIATION
IN-VITRO
CELLS
Developmental Biology
06 Biological Sciences
11 Medical And Health Sciences
Publication Status
Published