Linear stability analysis of morphodynamics during tissue regeneration in plants
Author(s)
Reijne, Anne-Mieke
Bordeu, Ignacio
Pruessner, Gunnar
Sena, Giovanni
Type
Journal Article
Abstract
One of the key characteristics of multicellular organisms is the ability to establish and maintain shapes, or morphologies, under a variety of physical and chemical perturbations. A quantitative description of the underlying morphological dynamics is a critical step to fully understand the self-organising properties of multicellular systems. Although many powerful mathematical tools have been developed to analyse stochastic dynamics, rarely these are applied to experimental developmental biology.
Here, we take root tip regeneration in the plant model system Arabidopsis thaliana as an example of robust morphogenesis in living tissue, and present a novel approach to quantify and model the relaxation of the system to its unperturbed morphology. By generating and analysing time-lapse series of regenerating root tips captured with confocal microscopy, we are able to extract and model the dynamics of key morphological traits at cellular resolution. We present a linear stability analysis of its Markovian dynamics, with the stationary state representing the intact root in the space of morphological traits. This analysis suggests the intriguing co-existence of two distinct temporal scales during the process of root regeneration in Arabidopsis.
We discuss the possible biological implications of our specific results, and suggest future experiments to further probe the self-organising properties of living tissue.
Here, we take root tip regeneration in the plant model system Arabidopsis thaliana as an example of robust morphogenesis in living tissue, and present a novel approach to quantify and model the relaxation of the system to its unperturbed morphology. By generating and analysing time-lapse series of regenerating root tips captured with confocal microscopy, we are able to extract and model the dynamics of key morphological traits at cellular resolution. We present a linear stability analysis of its Markovian dynamics, with the stationary state representing the intact root in the space of morphological traits. This analysis suggests the intriguing co-existence of two distinct temporal scales during the process of root regeneration in Arabidopsis.
We discuss the possible biological implications of our specific results, and suggest future experiments to further probe the self-organising properties of living tissue.
Date Issued
2018-12-24
Date Acceptance
2018-12-05
Citation
Journal of Physics D: Applied Physics, 2018, 52 (8), pp.1-9
ISSN
0022-3727
Publisher
IOP Publishing
Start Page
1
End Page
9
Journal / Book Title
Journal of Physics D: Applied Physics
Volume
52
Issue
8
Copyright Statement
© 2018 IOP Publishing Ltd. This is an author-created, un-copyedited version of an article accepted for publication in Journal of Physics D: Applied Physics. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The definitive publisher authenticated version is available online at https://iopscience.iop.org/article/10.1088/1361-6463/aaf68e
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000454233400002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Subjects
Science & Technology
Physical Sciences
Physics, Applied
Physics
morphogenesis
Arabidopsis
regeneration
morphodynamics
plant roots
morphometrics
COMPUTATIONAL MORPHODYNAMICS
MODELS
Publication Status
Published
Article Number
ARTN 084002
Date Publish Online
2018-12-24