The IRAD and beyond: what have we unravelled so far?
File(s)
Accepted version
Author(s)
Yuan, Xun
Mitsis, Andreas
Tang, Yida
Nienaber, Christoph A
Type
Journal Article
Abstract
Acute aortic dissection is a life-threatening condition associated with high morbidity and mortality rates and a long history of challenges to both diagnose and manage this condition successfully. The International Registry of Acute Aortic Dissection (IRAD) was established in 1996 as a global database to understand this old disease better and improve care for dissection. IRAD initially targeted various areas including etiological factors of dissection, modes of presentation, clinical features, physical findings, imaging, management, and outcomes, and is currently branching out in more specific fields such as endovascular intervention, genetic profiling, and functional imaging. Although presenting symptoms and physical findings have not changed significantly over two decades, the widespread use of computed tomography is standard and has improved the diagnostic pathway. Moreover, more patients are managed with appropriate procedures, such as surgery in type A, and endovascular therapy in subsets of type B aortic dissection. With these ongoing improvements in swift diagnostic work-up and therapeutic care, fewer patients are not getting appropriate treatment and more patients survive once they reach hospital.
Date Issued
2017-09-06
Date Acceptance
2017-08-08
Citation
General Thoracic and Cardiovascular Surgery, 2017, 67 (1), pp.146-153
ISSN
1863-6713
Publisher
Springer
Start Page
146
End Page
153
Journal / Book Title
General Thoracic and Cardiovascular Surgery
Volume
67
Issue
1
Copyright Statement
© 2017 Springer-Verlag. The final publication is available at Springer via https://doi.org/10.1007/s11748-017-0817-6.
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000455139100021&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Subjects
Science & Technology
Life Sciences & Biomedicine
Cardiac & Cardiovascular Systems
Surgery
Cardiovascular System & Cardiology
Aortic dissection
Imaging techniques
Biomarker
Cardiovascular surgery
Endovascular management
ACUTE-AORTIC-DISSECTION
LONG-TERM SURVIVAL
INTERNATIONAL-REGISTRY
CLINICAL PRESENTATION
TRANSESOPHAGEAL ECHOCARDIOGRAPHY
COMPUTED-TOMOGRAPHY
ENDOVASCULAR REPAIR
INSIGHTS
OUTCOMES
MANAGEMENT
Publication Status
Published
Date Publish Online
2017-09-06