SNR enhancement in brillouin microspectroscopy using spectrum reconstruction
File(s)
Author(s)
Xiang, YuChen
Foreman, Matthew R
Torok, Peter
Type
Journal Article
Abstract
Brillouin spectroscopy can suffer from low signal-to-noise ratios (SNRs). Such low SNRs can render common data analysis protocols unreliable, especially for SNRs below ∼10. In this work we exploit two denoising algorithms, namely maximum entropy reconstruction (MER) and wavelet analysis (WA), to improve the accuracy and precision in determination of Brillouin shifts and linewidth. Algorithm performance is quantified using Monte-Carlo simulations and benchmarked against the Cramér-Rao lower bound. Superior estimation results are demonstrated even at low SNRs (≥ 1). Denoising is furthermore applied to experimental Brillouin spectra of distilled water at room temperature, allowing the speed of sound in water to be extracted. Experimental and theoretical values were found to be consistent to within ±1% at unity SNR.
Date Issued
2020-02-01
Date Acceptance
2020-01-10
Citation
Biomedical Optics Express, 2020, 11 (2), pp.1020-1031
ISSN
2156-7085
Publisher
Optical Society of America
Start Page
1020
End Page
1031
Journal / Book Title
Biomedical Optics Express
Volume
11
Issue
2
Copyright Statement
© 2020 Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License. Further
distribution of this work must maintain attribution to the author(s) and the published article’s title, journal
citation, and DOI.
distribution of this work must maintain attribution to the author(s) and the published article’s title, journal
citation, and DOI.
License URL
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000519069700035&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Subjects
Science & Technology
Life Sciences & Biomedicine
Physical Sciences
Biochemical Research Methods
Optics
Radiology, Nuclear Medicine & Medical Imaging
Biochemistry & Molecular Biology
SINGLE-MOLECULE LOCALIZATION
IMAGE-RECONSTRUCTION
SPECTROSCOPY
MICROSCOPY
SCATTERING
SIZE
Publication Status
Published
Date Publish Online
2020-01-22