Referral for specialist follow-up and its association with post-discharge mortality among patients with systolic heart failure (from the National Heart Failure Audit for England and Wales)
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Published version
Author(s)
Type
Journal Article
Abstract
For patients admitted with worsening heart failure (HF), early follow-up after discharge is recommended. Whether outcomes can be improved when follow-up is done by cardiologists is uncertain. We aimed to determine the association between cardiology follow-up and risk of death for patients with HF discharged from hospital. Using data from the National Heart Failure Audit (England and Wales), we investigated the effect of referral to cardiology follow-up on 30-day and 1-year mortality in 68,772 patients with HF and a reduced left ventricular ejection fraction discharged from 185 hospitals from 2007 to 2013. The primary analyses used instrumental variable analysis complemented by hierarchical logistic and propensity-matched models. At the hospital level, rates of referral to cardiologists varied from 6% to 96%. The median odds ratio (OR) for referral to cardiologist was 2.3 (95% confidence interval [CI] 2.1 to 2.5), suggesting that, on average, the odds of a patient being referred for cardiologist follow-up after discharge differed ∼2.3 times from one randomly selected hospital to another one. Based on the proportion of patients (per region) referred for cardiology follow-up, referral for cardiology follow-up was associated with lower 30-day (OR 0.70; 95% CI 0.55 to 0.89) and 1-year mortality (OR 0.81; 95% CI 0.68 to 0.95) compared with no plans for cardiology follow-up (i.e., standard follow-up done by family doctors). Results from hierarchical logistic models and propensity-matched models were consistent (30-day mortality OR 0.66; 95% CI 0.61 to 0.72 and 0.66; 95% CI 0.58 to 0.76 for hierarchical and propensity matched models, respectively). For patients with HF and a reduced left ventricular ejection fraction admitted to hospital with worsening symptoms, referral to cardiology services for follow-up after discharge is strongly associated with reduced mortality, both early and late.
Date Issued
2016-11-01
Date Acceptance
2016-10-04
Citation
American Journal of Cardiology, 2016, 119 (3), pp.440-444
ISSN
1879-1913
Publisher
Elsevier
Start Page
440
End Page
444
Journal / Book Title
American Journal of Cardiology
Volume
119
Issue
3
Copyright Statement
© 2016 The Authors. Published by Elsevier Inc.
This is an open access article under the CC BY-NC-ND license (
http://creativecommons.
org/licenses/by-nc-nd/4.0/
).
This is an open access article under the CC BY-NC-ND license (
http://creativecommons.
org/licenses/by-nc-nd/4.0/
).
Sponsor
Royal Brompton & Harefield NHS Foundation Trust
National Institute for Health Research
National Institute for Health Research
Identifier
http://www.ncbi.nlm.nih.gov/pubmed/27884420
PII: S0002-9149(16)31732-5
Grant Number
N/A
N/A
HER00280
Subjects
Cardiovascular System & Hematology
1102 Cardiovascular Medicine And Haematology
Publication Status
Published
Coverage Spatial
United States