Influence of left atrial geometry on rotor core trajectories in a model of atrial fibrillation
File(s)
Accepted version
Author(s)
Type
Conference Paper
Abstract
Left atrial anatomy and myocardial architecture are
known to influence rotor initiation and maintenance.
However, identifying their relative contribution clinically
is challenging. The present study aims to investigate in
silico the effect of left atrial geometry in isolation on
rotor generation and evolution through the
spatiotemporal tracking of phase singularities. After
meandering for a short period of time, rotors are
attracted to specific areas of the chamber where there is
high curvature, primarily near the base of the left atrial
appendage and the junctions of the pulmonary veins. This
suggests that the left atrial anatomy could play a key role
in the perpetuation of fibrillatory activity.
known to influence rotor initiation and maintenance.
However, identifying their relative contribution clinically
is challenging. The present study aims to investigate in
silico the effect of left atrial geometry in isolation on
rotor generation and evolution through the
spatiotemporal tracking of phase singularities. After
meandering for a short period of time, rotors are
attracted to specific areas of the chamber where there is
high curvature, primarily near the base of the left atrial
appendage and the junctions of the pulmonary veins. This
suggests that the left atrial anatomy could play a key role
in the perpetuation of fibrillatory activity.
Date Issued
2015-09-09
Date Acceptance
2015-09-01
Citation
Computing in Cardiology, 2015, (42), pp.481-484
ISBN
978-1-5090-0685-4
ISSN
2325-8861
Publisher
IEEE
Start Page
481
End Page
484
Journal / Book Title
Computing in Cardiology
Issue
42
Copyright Statement
© 2015 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Sponsor
British Heart Foundation
Engineering & Physical Science Research Council (E
British Heart Foundation
Grant Number
RE/08/002
EP/L000407/1
Source
Computing in Cardiology
Publication Status
Published
Start Date
2015-09-06
Finish Date
2015-09-09
Coverage Spatial
Nice, France