Interleukins in urine and blood as markers of infection and risk factors for systemic problems
File(s)
Published version
Author(s)
Luxton, Richard
Kiely, Janice
Drake, Marcus
Type
Journal Article
Abstract
Interleukins are a diverse group of cytokines that play a crucial role in controlling immune responses and have potential as biomarkers. This mini review evaluates 12 recent papers linking urinary interleukins to both urinary infection and systemic diseases. While measurement of serum interleukins can indicate systemic inflammation, urinary interleukins provide more specific insights into renal or urinary tract inflammation. Urinary interleukins such as IL-8, IL-18, and IL-1β show promise for diagnosing urinary tract infections and other conditions. However, their diagnostic utility is complicated by their wide distribution in the body and patient-related factors. Advances in analytical techniques have enhanced the sensitivity and speed of interleukin measurement, improving their clinical utility.
Date Issued
2024-09
Date Acceptance
2024-09-20
Citation
European Urology Focus, 2024, 10 (5), pp.706-709
ISSN
2405-4569
Publisher
Elsevier
Start Page
706
End Page
709
Journal / Book Title
European Urology Focus
Volume
10
Issue
5
Copyright Statement
© 2024 The Author(s). Published by Elsevier B.V. on behalf of European Association of Urology. This is an open access article
under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
License URL
Identifier
https://www.sciencedirect.com/science/article/pii/S2405456924001834
Publication Status
Published
Date Publish Online
2024-10-05