Atopic Dermatitis and Respiratory Allergy: What is the Link
File(s)
Author(s)
Belgrave, DCM
Simpson, A
Buchan, I
Custovic A
Type
Journal Article
Abstract
Understanding the aetiology and progression of atopic dermatitis and respiratory allergy may elucidate early preventative and management strategies aimed towards reducing the global burden of asthma and allergic disease. In this article, we review the current opinion concerning the link between atopic dermatitis and the subsequent progression of respiratory allergies during childhood and into early adolescence. Advances in machine learning and statistical methodology have facilitated the discovery of more refined definitions of phenotypes for identifying biomarkers. Understanding the role of atopic dermatitis in the development of respiratory allergy may ultimately allow us to determine more effective treatment strategies, thus reducing the patient and economic burden associated with these conditions.
Date Issued
2015-09-28
Date Acceptance
2015-09-28
Citation
Current Dermatology Reports
ISSN
2162-4933
Publisher
Springer Verlag (Germany)
Start Page
221
End Page
227
Journal / Book Title
Current Dermatology Reports
Volume
4
Issue
4
Copyright Statement
© Springer Science+Business Media New York 2015. This is an open access article available under the CC-BY licence 4.0 (https://creativecommons.org/licenses/by/4.0/)
Sponsor
Medical Research Council (MRC)
Identifier
http://www.ncbi.nlm.nih.gov/pubmed/26566461
PII: 121
Grant Number
MR/M015181/1
Subjects
Asthma
Atopic dermatitis
Biomarker identification
Dermatology
Respiratory allergy
Review
Statistical machine learning
Stratified and personalised medicine strategies
Publication Status
Published
Coverage Spatial
United States