Rhabdomyolysis after COVID-19 infection: a case report and review of the literature
File(s)viruses-14-02255.pdf (921.06 KB)
Published version
Author(s)
Type
Journal Article
Abstract
Rhabdomyolysis is a condition in which muscle breaks down potentially leading to renal dysfunc-tion, and often occurs secondary to a precipitating factor. Viral or bacterial infections are common precipitants for initiating rhabdomyolysis. Recently, healthcare systems across the world have been challenged by a pandemic of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) causing ‘coronavirus disease 2019’ (COVID-19) disease. SARS-CoV-2 infection is recognized to cause respiratory and cardiovascular compromise, thromboembolic events, and acute kidney injury (AKI), however it is not known whether it can precipitate rhabdomyolysis, with only a limited number of cases of SARS-CoV-2 infection preceding rhabdomyolysis reported to date. Here, we report the case of a 64-year old woman who developed rhabdomyolysis shortly after SARS-CoV-2 infection and COVID-19. She initially presented with muscular pain, a creatine kinase level of 119,301 IU/L, and a mild rise in her creatinine level to 92 µmol/L, but successfully recovered with intravenous fluid support. We also review the literature to summarise previously reported cases of rhabdomyolysis precipitated by SARS-CoV-2, highlighting the need to consider this diagnosis in patients presenting with SARS-CoV-2 and myalgia.
Date Issued
2022-10-08
Date Acceptance
2022-10-08
Citation
Viruses, 2022, 14 (10), pp.1-10
ISSN
1999-4915
Publisher
MDPI AG
Start Page
1
End Page
10
Journal / Book Title
Viruses
Volume
14
Issue
10
Copyright Statement
© 2022 by the authors.
Licensee MDPI, Basel, Switzerland.
This article is an open access article
distributed under the terms and
conditions of the Creative Commons
Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Licensee MDPI, Basel, Switzerland.
This article is an open access article
distributed under the terms and
conditions of the Creative Commons
Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
License URL
Sponsor
National Institute for Health Research
Identifier
https://www.mdpi.com/1999-4915/14/10/2255
Grant Number
CS-2018-18-ST2-002
Subjects
Science & Technology
Life Sciences & Biomedicine
Virology
rhabdomyolysis
viral-induced rhabdomyolysis
COVID-19 disease
SARS-CoV-2 infection
INFLUENZA VACCINE
DIAGNOSIS
PATIENT
COVID-19 disease
SARS-CoV-2 infection
rhabdomyolysis
viral-induced rhabdomyolysis
Humans
Female
Middle Aged
COVID-19
SARS-CoV-2
Creatinine
Rhabdomyolysis
Myalgia
Creatine Kinase
Humans
Rhabdomyolysis
Creatinine
Creatine Kinase
Middle Aged
Female
Myalgia
COVID-19
SARS-CoV-2
0605 Microbiology
Publication Status
Published
Date Publish Online
2022-10-14