Uniting mathematics and biology for control of visceral leishmaniasis
File(s)Trends in Parasitology_2015.pdf (729.14 KB)
Published version
Author(s)
Type
Journal Article
Abstract
The neglected tropical disease (NTD) visceral leishmaniasis (VL) has been targeted by the WHO for elimination as a public health problem on the Indian subcontinent by 2017 or earlier. To date there is a surprising scarcity of mathematical models capable of capturing VL disease dynamics, which are widely considered central to planning and assessing the efficacy of interventions. The few models that have been developed are examined, highlighting the necessity for better data to parameterise and fit these and future models. In particular, the characterisation and infectiousness of the different disease stages will be crucial to elimination. Modelling can then assist in establishing whether, when, and how the WHO VL elimination targets can be met.
Date Issued
2015-04-22
Date Acceptance
2015-04-22
Citation
Trends in Parasitology, 2015, 31 (6), pp.251-259
ISSN
1471-5007
Publisher
Elsevier
Start Page
251
End Page
259
Journal / Book Title
Trends in Parasitology
Volume
31
Issue
6
Copyright Statement
© 2015 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
License URL
Publication Status
Accepted