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  5. A conformable holographic sensing bandage for wound monitoring
 
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A conformable holographic sensing bandage for wound monitoring
File(s)
Adv Funct Materials - 2024 - Zhang - A Conformable Holographic Sensing Bandage for Wound Monitoring.pdf (4.92 MB)
Published version
Author(s)
Zhang, Yihan
Hu, Yubing
Montelongo, Yunuen
Hsu, Mintin
Blyth, Jeff
more
Type
Journal Article
Abstract
Chronic wound monitoring can provide personalized pathophysiological information for wound management and treatment. Continuously monitoring the wound milieu via the holographic pH sensor can reflect the wound healing processes. However, the integration with wearable devices is hindered by its inherently restricted interrogation angle dependency within 5°. Herein, a ball bearing-based double photopolymerization method is developed to fabricate holographic pH sensors with a broader interrogation angle range of 15°–60° in wound exudates. The fabricated holographic pH sensor is then integrated with the flexible ultrathin polyurethane substrate, which replays a total Bragg peak shift of approximately 150 nm with physiological pH changes from 7.00 to 8.75. The conformable holographic pH sensing bandages demonstrate the ability to quantify the pH value under various bending manipulations, simulating the mounting on the body surface. The reversibility in artificial wound exudate demonstrates the durability and capability of real-time pH monitoring in the wound milieu with minimal effect on the replay wavelength. The addition of electrolytes, albumin, urea, uric acid, lactate, and glucose does not interfere with the readout over the physiological pH range of wound exudates. The obtained conformable holographic sensing bandage benefits the wound healing process monitoring through colorimetric interrogation at point-of-care (POC) settings.
Date Issued
2024-04-18
Date Acceptance
2024-01-01
Citation
Advanced Functional Materials, 2024, 34 (16)
URI
http://hdl.handle.net/10044/1/110062
URL
http://dx.doi.org/10.1002/adfm.202308490
DOI
https://www.dx.doi.org/10.1002/adfm.202308490
ISSN
1616-301X
Publisher
Wiley
Journal / Book Title
Advanced Functional Materials
Volume
34
Issue
16
Copyright Statement
© 2024 The Authors. Advanced Functional Materials published by Wiley-VCH GmbH

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
License URL
https://creativecommons.org/licenses/by/4.0/
Identifier
http://dx.doi.org/10.1002/adfm.202308490
Publication Status
Published
Article Number
2308490
Date Publish Online
2024-01-07
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