Therapeutic hypothermia in mild neonatal encephalopathy: a national survey of practice in the UK
File(s)MildHIE_UKSurvey_Revised_Clean.pdf (137.92 KB)
Accepted version
Author(s)
Type
Journal Article
Abstract
Although major cooling trials (and subsequent guidelines) excluded babies with mild encephalopathy, anecdotal evidence suggests that cooling is often offered to these infants. We report a national survey on current cooling practices for babies with mild encephalopathy in the UK. From 74 neonatal units contacted, 68 were cooling centres. We received 54 responses (79%) and included 48 (five excluded due to incomplete data and one found later not to offer cooling). Of these, 36 centres (75%) offered cooling to infants with mild encephalopathy. Although most of the participating units reported targeting 33-34°C core temperature, seven (19%) considered initiating cooling beyond 6 hours of age and 13 (36%) discontinued cooling prior to 72 hours. Babies were ventilated for cooling in two (6%) units and 13 (36%) sedated all cooled babies. Enteral feeding was withheld in 15 (42%) units and reduced below 25% of requirements in eight (22%) units. MRI and neurodevelopmental outcome evaluation were offered to all cooled babies in 29 (80%) and 27 (75%) units, respectively. Further research is necessary to ensure optimal neuroprotection in mild encephalopathy.
Date Issued
2017-09-23
Date Acceptance
2017-08-30
Citation
Archives of Disease in Childhood. Fetal and Neonatal Edition, 2017, 103, pp.F388-F390
ISSN
1359-2998
Publisher
BMJ Publishing Group
Start Page
F388
End Page
F390
Journal / Book Title
Archives of Disease in Childhood. Fetal and Neonatal Edition
Volume
103
Copyright Statement
© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
Sponsor
Imperial College Healthcare NHS Trust- BRC Funding
Imperial College Healthcare NHS Trust- BRC Funding
National Institute for Health Research
National Institute for Health Research
Imperial College Healthcare NHS Trust
Medical Research Council (MRC)
Identifier
PII: archdischild-2017-313320
Grant Number
RDD01 79560
RDD01 79560
NIHR/CS/010/022
n/a
RDD10
MR/R001375/1
Subjects
neonatal encephalopathy
therapeutic hypothermia
Publication Status
Published