Molecular Structure Influences the Stability of Membrane Penetrating Biointerfaces.
File(s)
Accepted version
Author(s)
Almquist, BD
Melosh, NA
Type
Journal Article
Abstract
Nanoscale patterning of hydrophobic bands on otherwise hydrophilic surfaces allows integration of inorganic structures through biological membranes, reminiscent of transmembrane proteins. Here we show that a set of innate molecular properties of the self-assembling hydrophobic band determine the resulting interface stability. Surprisingly, hydrophobicity is found to be a secondary factor with monolayer crystallinity the major determinate of interface strength. These results begin to establish guidelines for seamless bioinorganic integration of nanoscale probes with lipid membranes.
Date Issued
2011-05-11
Date Acceptance
2011-03-25
Citation
Nano Letters, 2011, 11 (5), pp.2066-2070
ISSN
1530-6984
Start Page
2066
End Page
2070
Journal / Book Title
Nano Letters
Volume
11
Issue
5
Copyright Statement
© 2011 American Chemical Society. This document is the Accepted Manuscript version of a Published Work that appeared in final form in Nano Letters, after peer review and technical editing by the publisher. To access the final edited and published work see: http://pubs.acs.org/doi/abs/10.1021/nl200542m
Description
20.07.15 KB. Ok to add accepted version, 12 months embargo expired.