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Boosting dissolution-dynamic nuclear polarization by multiple-step dipolar order mediated 1H→13C cross-polarization
File(s)
Author(s)
Elliott, Stuart J
Cala, Olivier
Stern, Quentin
Cousin, Samuel F
Ceillier, Morgan
Type
Journal Article
Abstract
Dissolution-dynamic nuclear polarization can be boosted by employing multiple-contact cross-polarization techniques to transfer polarization from 1H to 13C spins. The method is efficient and significantly reduces polarization build-up times, however, it involves high-power radiofrequency pulses in a superfluid helium environment which limit its implementation and applicability and prevent a significant scaling-up of the sample size. We propose to overcome this limitation by a stepwise transfer of polarization using a low-energy and low-peak power radiofrequency pulse sequence where the 1H→13C polarization transfer is mediated by a dipolar spin order reservoir. An experimental demonstration is presented for [1-13C]sodium acetate. A solid-state 13C polarization of ∼43.5% was achieved using this method with a build-up time constant of ∼5.1 minutes, leading to a ∼27.5% 13C polarization in the liquid-state after sample dissolution. The low-power multiple-step polarization transfer efficiency achieved with respect to the most advanced and highest-power multiple-contact cross-polarization approach was found to be ∼0.69.
Date Issued
2021-12-01
Date Acceptance
2021-07-23
Citation
Journal of Magnetic Resonance Open, 2021, 8-9
URI
URL
DOI
ISSN
2666-4410
Publisher
Elsevier
Journal / Book Title
Journal of Magnetic Resonance Open
Volume
8-9
Copyright Statement
© 2021 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0/)
License URL
Identifier
10.1016/j.jmro.2021.100018
Subjects
Biochemical Research Methods
Biochemistry & Molecular Biology
CP
dCP
dDNP
Dissolution
DNP
Hyperpolarization
Life Sciences & Biomedicine
MAGNETIC-RESONANCE
NMR
Physical Sciences
Physics
Physics, Atomic, Molecular & Chemical
Science & Technology
SIGNAL
SOLIDS
Spectroscopy
SPECTROSCOPY
Technology
TEMPERATURES
WATER
ZEEMAN
Publication Status
Published
Article Number
ARTN 100018
Date Publish Online
2021-07-25