Antibody response to SARS-CoV-2 infection is not associated with Post-COVID-19 Syndrome in healthcare workers
File(s)jiab120.pdf (2.15 MB)
Published version
Author(s)
Pereira, Christopher
Harris, Benjamin
Di Giovannantonio, Matteo
Rosadas, Carolina
Short, Charlotte-Eve
Type
Journal Article
Abstract
It is currently unknown how Post-COVID-19 Syndrome (PCS) may affect those infected with SARS-CoV-2. This longitudinal study reports on healthcare staff who tested positive for SARS-CoV-2 between March-April 2020 and follows their antibody titres and symptomatology. Over half (n=21/38) had PCS at 7-8 months. There was no statistically significant difference between initial RT-PCR viral titres or serial antibody levels between those who did and did not develop PCS. This study highlights the relative commonality of PCS in healthcare workers and this should be considered in vaccination scheduling and workforce planning to allow adequate frontline staffing numbers.
Date Issued
2021-04-28
Date Acceptance
2021-02-26
Citation
Journal of Infectious Diseases, 2021, 223 (10), pp.1671-1676
ISSN
0022-1899
Publisher
Oxford University Press (OUP)
Start Page
1671
End Page
1676
Journal / Book Title
Journal of Infectious Diseases
Volume
223
Issue
10
Copyright Statement
© The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America.
This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
Identifier
https://academic.oup.com/jid/article/223/10/1671/6155862
Subjects
COVID-19
Healthcare workers
Imperial Hybrid DABA
Long-COVID
Post–COVID-19 Syndrome
SARS-CoV-2
multidisciplinary team
Microbiology
06 Biological Sciences
11 Medical and Health Sciences
Publication Status
Published
Date Publish Online
2021-03-02