Novel Denisovan and Neanderthal Retroviruses
File(s)Novel Denisovan and Neanderthal retroviruses.pdf (670.13 KB)
Published version
Author(s)
Type
Journal Article
Abstract
Following the recent availability of high-coverage genomes for Denisovan and Neanderthal hominids, we conducted a screen for endogenized retroviruses, identifying six novel, previously unreported HERV-K(HML2) elements (HERV-K is human endogenous retrovirus K). These elements are absent from the human genome (hg38) and appear to be unique to archaic hominids. These findings provide further evidence supporting the recent activity of the HERV-K(HML2) group, which has been implicated in human disease. They will also provide insights into the evolution of archaic hominids.
Date Issued
2014-08-20
Date Acceptance
2014-08-18
Citation
Journal of Virology, 2014, 88 (21), pp.12907-12909
ISSN
1098-5514
Publisher
American Society for Microbiology
Start Page
12907
End Page
12909
Journal / Book Title
Journal of Virology
Volume
88
Issue
21
Copyright Statement
© 2014 Lee et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license.
Subjects
Science & Technology
Life Sciences & Biomedicine
Virology
GENOME SEQUENCE
Animals
Endogenous Retroviruses
Female
Fossils
Genome
Hominidae
06 Biological Sciences
07 Agricultural And Veterinary Sciences
11 Medical And Health Sciences
Publication Status
Published