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  5. A global effort to define the human genetics of protective immunity to SARS-CoV-2 infection.
 
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A global effort to define the human genetics of protective immunity to SARS-CoV-2 infection.
File(s)
COVID HGE CELL[2].pdf (957.56 KB)
Accepted version
Author(s)
Casanova, Jean-Laurent
Su, Helen C
COVID Human Genetic Effort
Type
Journal Article
Abstract
SARS-CoV-2 infection displays immense inter-individual clinical variability, ranging from silent infection to lethal disease. The role of human genetics in determining clinical response to the virus remains unclear. Studies of outliers-individuals remaining uninfected despite viral exposure and healthy young patients with life-threatening disease-present a unique opportunity to reveal human genetic determinants of infection and disease.
Date Issued
2020-06-11
Date Acceptance
2020-05-01
Citation
Cell, 2020, 181 (6), pp.1194-1199
URI
http://hdl.handle.net/10044/1/82074
URL
https://www.sciencedirect.com/science/article/pii/S0092867420306115?via%3Dihub
DOI
https://www.dx.doi.org/10.1016/j.cell.2020.05.016
ISSN
0092-8674
Publisher
Elsevier
Start Page
1194
End Page
1199
Journal / Book Title
Cell
Volume
181
Issue
6
Copyright Statement
2020 © Elsevier Ltd. All rights reserved. This manuscript is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence http://creativecommons.org/licenses/by-nc-nd/4.0/
License URL
https://creativecommons.org/licenses/by-nc-nd/4.0/
Sponsor
UKRI Future Leader's Fellowship
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/32405102
PII: S0092-8674(20)30611-5
Subjects
Age Factors
Betacoronavirus
Coronavirus Infections
Disease Resistance
Genetic Association Studies
Genetic Diseases, Inborn
Genetic Predisposition to Disease
Genetic Variation
Genome, Human
Host-Pathogen Interactions
Humans
Infections
Pandemics
Pneumonia, Viral
Publication Status
Published
Coverage Spatial
United States
Date Publish Online
2020-05-13
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