A phase model of temperature-dependent mammalian cold receptors
File(s)coldrec_preprint.pdf (1.16 MB)
Accepted version
Author(s)
Roper, Peter
Bressloff, Paul C
Longtin, André
Type
Journal Article
Abstract
We present a tractable stochastic phase model of the temperature sensitivity of a mammalian cold receptor. Using simple linear dependencies of the amplitude, frequency, and bias on temperature, the model reproduces the experimentally observed transitions between bursting, beating, and stochastically phase-locked firing patterns. We analyze the model in the deterministic limit and predict, using a Strutt map, the number of spikes per burst for a given temperature. The inclusion of noise produces a variable number of spikes per burst and also extends the dynamic range of the neuron, both of which are analyzed in terms of the Strutt map. Our analysis can be readily applied to other receptors that display various bursting patterns following temperature changes.
Date Issued
2000-05
Date Acceptance
1999-06-14
Citation
Neural Computation, 2000, 12 (5), pp.1067-1093
ISSN
0899-7667
Publisher
Massachusetts Institute of Technology Press
Start Page
1067
End Page
1093
Journal / Book Title
Neural Computation
Volume
12
Issue
5
Copyright Statement
© 2000 Massachusetts Institute of Technology Peter Roper, Paul C. Bressloff, André Longtin; A Phase Model of Temperature-Dependent Mammalian Cold Receptors. Neural Comput 2000; 12 (5): 1067–1093. doi: https://doi.org/10.1162/089976600300015510
Identifier
http://dx.doi.org/10.1162/089976600300015510
Publication Status
Published
Date Publish Online
2000-05-01