Changing prevalence of current asthma and inhaled corticosteroid treatment in the UK: population based cohort 2006 to 2016
File(s)
Author(s)
Bloom, Chloe
Saglani, sejal
Feary, johanna
Jarvis, debbie
Quint, jennifer
Type
Journal Article
Abstract
BACKGROUND:
Asthma is the most common respiratory disorder in the UK, yet we have incomplete knowledge on the prevalence of current disease, treatment and exacerbations.
METHODS:
We used UK electronic healthcare records, 2006 to 2016, to estimate the prevalence of current asthma by year, gender and age (<5, 5-11, 12-17, 18-24, 25-54 and ≥55 years), and the proportion prescribed inhaled corticosteroids (ICS) and additional asthma-therapy, treated for exacerbations and other asthma care markers.
RESULTS:
Overall current asthma prevalence was 6.5% in 2016 (7.2% in 2006). Prevalence fell in those under 45 years. The lowest prevalence and largest absolute decrease was in children under 5-years. In 2016, 80% of current asthma patients were managed on ICS, (65% in 2006); this increase occurred in all ages, primarily due to an increase in low-dose ICS. During this time there was an increase in all age-groups in the proportion prescribed additional asthma-therapy, treated for an exacerbation within primary care, given an annual asthma review or management plan. Hospitalised exacerbations showed minimal change over time.
CONCLUSION:
Asthma remains highly prevalent and a significant healthcare burden. In those with a diagnosis, there was an increase in ICS prescriptions and treatment of exacerbations across all age-groups. This may reflect a trend towards more aggressive asthma management within primary care. An apparent decline in prevalence was observed in those aged under 45 years, particularly in children under 5 years.
Asthma is the most common respiratory disorder in the UK, yet we have incomplete knowledge on the prevalence of current disease, treatment and exacerbations.
METHODS:
We used UK electronic healthcare records, 2006 to 2016, to estimate the prevalence of current asthma by year, gender and age (<5, 5-11, 12-17, 18-24, 25-54 and ≥55 years), and the proportion prescribed inhaled corticosteroids (ICS) and additional asthma-therapy, treated for exacerbations and other asthma care markers.
RESULTS:
Overall current asthma prevalence was 6.5% in 2016 (7.2% in 2006). Prevalence fell in those under 45 years. The lowest prevalence and largest absolute decrease was in children under 5-years. In 2016, 80% of current asthma patients were managed on ICS, (65% in 2006); this increase occurred in all ages, primarily due to an increase in low-dose ICS. During this time there was an increase in all age-groups in the proportion prescribed additional asthma-therapy, treated for an exacerbation within primary care, given an annual asthma review or management plan. Hospitalised exacerbations showed minimal change over time.
CONCLUSION:
Asthma remains highly prevalent and a significant healthcare burden. In those with a diagnosis, there was an increase in ICS prescriptions and treatment of exacerbations across all age-groups. This may reflect a trend towards more aggressive asthma management within primary care. An apparent decline in prevalence was observed in those aged under 45 years, particularly in children under 5 years.
Date Issued
2019-04-01
Date Acceptance
2019-01-07
Citation
European Respiratory Journal, 2019, 53 (4), pp.1-8
ISSN
0903-1936
Publisher
European Respiratory Society
Start Page
1
End Page
8
Journal / Book Title
European Respiratory Journal
Volume
53
Issue
4
Copyright Statement
Copyright ©ERS 2019 https://www.ersjournals.com/user-licence
Identifier
https://erj.ersjournals.com/content/53/4/1802130
Subjects
Science & Technology
Life Sciences & Biomedicine
Respiratory System
CHILDHOOD
SYMPTOMS
INCREASE
TRENDS
CARE
Administration, Inhalation
Adolescent
Adrenal Cortex Hormones
Adult
Asthma
Child
Child, Preschool
Cohort Studies
Female
Humans
Male
Middle Aged
Prevalence
United Kingdom
Young Adult
Humans
Asthma
Adrenal Cortex Hormones
Administration, Inhalation
Prevalence
Cohort Studies
Adolescent
Adult
Middle Aged
Child
Child, Preschool
Female
Male
Young Adult
United Kingdom
11 Medical and Health Sciences
Respiratory System
Publication Status
Published
Article Number
1802130
Date Publish Online
2019-04-04