Reconciling Epigenetic Memory and Transcriptional Responsiveness

Fisher, AG; Stumpf, MPH; Merkenschlager, M

doi:https://www.dx.doi.org/10.1016/j.cels.2017.04.005

File(s)

Cell Systems - Fisher on Berry revised (002).pdf (194.43 KB)

Accepted version

Author(s)

Fisher, AG

Stumpf, MPH

Merkenschlager, M

Type

Journal Article

Abstract

The molecular basis of cellular memory is important but poorly understood. Using estimates of histone dynamics, Martin Howard and colleagues construct a mathematical model that helps to explain both the stability and flexibility of Polycomb-mediated gene regulation in cellular memory.

Date Issued

2017-04-26

Date Acceptance

2017-04-01

Citation

CELL SYSTEMS, 2017, 4 (4), pp.373-374

URI

http://hdl.handle.net/10044/1/48672

DOI

https://www.dx.doi.org/10.1016/j.cels.2017.04.005

ISSN

2405-4712

Publisher

CELL PRESS

Start Page

373

End Page

374

Journal / Book Title

CELL SYSTEMS

Volume

4

Issue

4

Copyright Statement

© 2017 Elsevier Inc. All rights reserved. This manuscript is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/

Identifier

http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000402747300002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Subjects

Science & Technology

Life Sciences & Biomedicine

Biochemistry & Molecular Biology

Cell Biology

PROPAGATION

Publication Status

Published