Comparison of arterial wave intensity analysis by pressure-velocity and diameter-velocity methods in a virtual population of adult subjects.
File(s)comparison-of-WI resubmitted.pdf (920.71 KB)
Accepted version
Author(s)
Reavette, Ryan M
Sherwin, Spencer J
Tang, Mengxing
Weinberg, Peter D
Type
Journal Article
Abstract
Pressure-velocity-based analysis of arterial wave intensity gives clinically relevant information about the performance of the heart and vessels, but its utility is limited because accurate pressure measurements can only be obtained invasively. Diameter-velocity-based wave intensity can be obtained noninvasively using ultrasound; however, due to the nonlinear relationship between blood pressure and arterial diameter, the two wave intensities might give disparate clinical indications. To test the magnitude of the disagreement, we have generated an age-stratified virtual population to investigate how the two dominant nonlinearities 'viscoelasticity and strain-stiffening' cause the two formulations to differ. We found strong agreement between the pressure-velocity and diameter-velocity methods, particularly for the systolic wave energy, the ratio between systolic and diastolic wave heights, and older subjects. The results are promising regarding the introduction of noninvasive wave intensities in the clinic.
Date Issued
2020-11-01
Date Acceptance
2020-03-22
Citation
Proceedings of the Institution of Mechanical Engineers Part H: Journal of Engineering in Medicine, 2020, 234 (11), pp.1260-1276
ISSN
0954-4119
Publisher
SAGE Publications
Start Page
1260
End Page
1276
Journal / Book Title
Proceedings of the Institution of Mechanical Engineers Part H: Journal of Engineering in Medicine
Volume
234
Issue
11
Copyright Statement
© IMechE 2020. The final, definitive version of this paper has been published in Reavette, R. M., Sherwin, S. J., Tang, M., & Weinberg, P. D. (2020). Comparison of arterial wave intensity analysis by pressure–velocity and diameter–velocity methods in a virtual population of adult subjects. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine by Sage Publications Ltd. All rights reserved. It is available at: https://doi.org/10.1177/0954411920926094
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/32650691
Subjects
Wave intensity analysis
one-dimensional computational modelling
pulse wave
systemic circulation
ultrasound
virtual population
Publication Status
Published
Coverage Spatial
England
Date Publish Online
2020-07-10