Tuning BODIPY molecular rotors into the red: sensitivity to viscosity vs. temperature
File(s)TTVu Red Bodipys.pdf (2.34 MB) TTVu Red Bodipys SI.pdf (1.15 MB)
Published version
Supporting information
Author(s)
Thanh, TV
Meallet-Renault, R
Clavier, G
Trofimov, BA
Kuimova, MK
Type
Journal Article
Abstract
Viscosity variations in the microscopic world are of paramount importance for diffusion and reactions. In the last decade a new class of fluorescent probes for measuring viscosity has emerged termed ‘molecular rotors’, which allows quantitative mapping of viscosity in microscopically heterogeneous environments. Here we attempt to tune the absorption and emission of one such ‘molecular rotor’ based on the BODIPY fluorescent core into the red region of the spectrum, to allow better compatibility with the ‘tissue optical window’ and imaging of cells and tissues. We consequently find that our red-emitting BODIPY fluorophores are sensitive to environmental temperature rather than to viscosity, thus suggesting a new prototype for a ‘molecular thermometer’.
Date Issued
2016-04-14
Date Acceptance
2015-10-30
Citation
Journal of Materials Chemistry C, 2016, 4 (14), pp.2828-2833
ISSN
2050-7534
Publisher
Royal Society of Chemistry
Start Page
2828
End Page
2833
Journal / Book Title
Journal of Materials Chemistry C
Volume
4
Issue
14
Copyright Statement
© The Royal Society of Chemistry 2015. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. (http://creativecommons.org/licenses/by/3.0/)
Sponsor
Engineering & Physical Science Research Council (EPSRC)
Engineering & Physical Science Research Council (EPSRC)
Commission of the European Communities
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000373611700019&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Grant Number
EP/I003983/1
EP/K030760/1
302441
Subjects
Science & Technology
Technology
Physical Sciences
Materials Science, Multidisciplinary
Physics, Applied
Materials Science
Physics
Live cells
Fluorescence
Substituents
Membranes
Sensor
Probe
Publication Status
Published
Date Publish Online
2015-11-09