Mueller polarimetric imaging for surgical and diagnostic applications: a review
File(s)review manuscript revision 4.0.pdf (1.78 MB)
Accepted version
Author(s)
Qi, J
Elson, D
Type
Journal Article
Abstract
Polarization
is a fundamental property of light
and
a powerful
se
n
sing tool that has been applied to many areas. A Mueller
matrix is a complete
mathematical description of the
polarization characteristics of objects that interact with light
,
and is known as a transfer function of Stokes vectors which
characterise the state of polari
z
ation of light. Mueller
polarimetric imaging measures Mueller mat
rices over a field
of view and thus allows for visualising the polarization
characteristics of the objects. It has emerged as a promising
technique in recent years for tissue imaging, improving image
contrast
a
nd providing
a unique perspective to reveal additional information that cannot be resolved by other optical imaging modalities. This review introduces the basis of the Stokes-Mueller formulism, interpretation methods of Mueller matrices into fundamental polarization properties, polarization properties of biological tissues, and
considerations in the construction of Mueller polarimetric
imaging devices for surgical and diagnostic applications,
including primary configurations, optimization procedures,
calibration methods as well as the instrument polarization
properties of several widely-used biomedical optical devices.
The paper also reviews recent progress in Mueller polarimetric endoscopes and fibre Mueller polarimeters, followed by the future outlook in applying the technique to surgery and diagnostics.
is a fundamental property of light
and
a powerful
se
n
sing tool that has been applied to many areas. A Mueller
matrix is a complete
mathematical description of the
polarization characteristics of objects that interact with light
,
and is known as a transfer function of Stokes vectors which
characterise the state of polari
z
ation of light. Mueller
polarimetric imaging measures Mueller mat
rices over a field
of view and thus allows for visualising the polarization
characteristics of the objects. It has emerged as a promising
technique in recent years for tissue imaging, improving image
contrast
a
nd providing
a unique perspective to reveal additional information that cannot be resolved by other optical imaging modalities. This review introduces the basis of the Stokes-Mueller formulism, interpretation methods of Mueller matrices into fundamental polarization properties, polarization properties of biological tissues, and
considerations in the construction of Mueller polarimetric
imaging devices for surgical and diagnostic applications,
including primary configurations, optimization procedures,
calibration methods as well as the instrument polarization
properties of several widely-used biomedical optical devices.
The paper also reviews recent progress in Mueller polarimetric endoscopes and fibre Mueller polarimeters, followed by the future outlook in applying the technique to surgery and diagnostics.
Date Issued
2017-08-01
Date Acceptance
2017-01-19
Citation
Journal of Biophotonics, 10 (8), pp.950-982
ISSN
1864-0648
Publisher
Wiley-VCH Verlag
Start Page
950
End Page
982
Journal / Book Title
Journal of Biophotonics
Volume
10
Issue
8
Copyright Statement
This is the peer reviewed version of the following article: J. Qi, D. S. Elson, J. Biophotonics 2017, 10, 950., which has been published in final form at https://dx.doi.org/10.1002/jbio.201600152. This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.
Sponsor
Commission of the European Communities
National Institute for Health Research
Grant Number
242991
II-LB-0214-20009
Subjects
Science & Technology
Life Sciences & Biomedicine
Physical Sciences
Biochemical Research Methods
Biophysics
Optics
Biochemistry & Molecular Biology
Polarimetric imaging Mueller polarimetry
tissue polarimetry
surgical imaging
Mueller polarimetric endoscopes
ELASTIC-SCATTERING SPECTROSCOPY
MATRIX DIFFERENTIAL DECOMPOSITION
OPTICAL COHERENCE TOMOGRAPHY
POLARIZED-LIGHT PROPAGATION
NERVE-FIBER LAYER
BIOLOGICAL TISSUES
IN-VIVO
TURBID MEDIA
DEPTH SELECTIVITY
4-DETECTOR PHOTOPOLARIMETER
Optoelectronics & Photonics
Publication Status
Published