A CMOS-Based Neural Implantable Optrode for Optogenetic Stimulation and Electrical Recording
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Accepted version
Author(s)
Type
Conference Paper
Abstract
This paper presents a novel integrated optrode for simultaneous optical stimulation and electrical recording for closed -loop optogenetic
neuro-prosthetic applications. The design has been implemented in
a commercially available 0.35μm CMOS process. The system includes circuits for controlling the optical stimulations; recording
local field potentials (LFPs); and onboard diagnostics. The neural interface has two clusters of stimulation and recording sites. Each stimulation site has a bonding point for connecting a micro light emitting diode (μLED) to deliver light to the targeted area of
brain tissue. Each recording site is designed to be post-processed with electrode materials to provide monitoring of
neural activity. On-chip diagnostic sensing has been included to provide real-time diagnostics for post-implantation and during normal operation.
neuro-prosthetic applications. The design has been implemented in
a commercially available 0.35μm CMOS process. The system includes circuits for controlling the optical stimulations; recording
local field potentials (LFPs); and onboard diagnostics. The neural interface has two clusters of stimulation and recording sites. Each stimulation site has a bonding point for connecting a micro light emitting diode (μLED) to deliver light to the targeted area of
brain tissue. Each recording site is designed to be post-processed with electrode materials to provide monitoring of
neural activity. On-chip diagnostic sensing has been included to provide real-time diagnostics for post-implantation and during normal operation.
Date Issued
2016-08-24
Date Acceptance
2015-08-10
Citation
Biomedical Circuits and Systems Conference (BioCAS), 2015 IEEE, 2016, pp.286-289
Publisher
IEEE
Start Page
286
End Page
289
Journal / Book Title
Biomedical Circuits and Systems Conference (BioCAS), 2015 IEEE
Copyright Statement
© 2015 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Sponsor
Wellcome Trust
Engineering & Physical Science Research Council (EPSRC)
Grant Number
BH134389
EP/M020975/1
Source
IEEE Biomedical Circuits and Systems (BioCAS) Conference
Publication Status
Published
Start Date
2015-10-22
Finish Date
2015-10-24
Coverage Spatial
Atlanta, Georgia, USA