An extended 3D whole-heart myocardial first-pass perfusion sequence: alternate-cycle views with isotropic and high-resolution imaging
File(s)
Published version
Author(s)
Fair, M
Gatehouse, P
DiBella, EVR
Chen, L
Firmin, DN
Type
Conference Paper
Abstract
Simultaneously optimising parameters such as LV cover-
age, image resolution and contrast sensitivity is difficult
in first-pass perfusion (FPP). 3D FPP shows potential (1)
to improve coverage, but
“
whole-heart
”
coverage
demands high acceleration forcing compromises such as
loss of spatial resolution. 2D FPP shows high diagnostic
ability with more slices distributed over alternate-RR
cycles (2), relaxing acceleration requirements. This work
proposes that 3D FPP could interleave two strategies
with different 3D parameters in alternate cycles, in sum
approaching the full set of desired FPP properties. This
work also aims to improve sp
ecificity against artefacts
by imaging the same myocardium with two different
interleaved 3D scans (distinct from reformatting a single
3D FPP scan). Similar confirmation strategies are often
used in CMR, such as repetition with swapped phase-
encode direction in late-enhancement imaging.
age, image resolution and contrast sensitivity is difficult
in first-pass perfusion (FPP). 3D FPP shows potential (1)
to improve coverage, but
“
whole-heart
”
coverage
demands high acceleration forcing compromises such as
loss of spatial resolution. 2D FPP shows high diagnostic
ability with more slices distributed over alternate-RR
cycles (2), relaxing acceleration requirements. This work
proposes that 3D FPP could interleave two strategies
with different 3D parameters in alternate cycles, in sum
approaching the full set of desired FPP properties. This
work also aims to improve sp
ecificity against artefacts
by imaging the same myocardium with two different
interleaved 3D scans (distinct from reformatting a single
3D FPP scan). Similar confirmation strategies are often
used in CMR, such as repetition with swapped phase-
encode direction in late-enhancement imaging.
Date Issued
2016-01-27
Date Acceptance
2016-01-27
Citation
Journal of Cardiovascular Magnetic Resonance, 2016, 18 (Suppl. 1)
ISSN
1532-429X
Publisher
BioMed Central
Journal / Book Title
Journal of Cardiovascular Magnetic Resonance
Volume
18
Issue
Suppl. 1
Copyright Statement
© Fair et al. 2016. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Sponsor
British Heart Foundation
British Heart Foundation
Royal Brompton & Harefield NHS Foundation Trust
Grant Number
FS/04/071
FS/13/21/30143
6004 D Firmin Research Associa
Source
Society for Cardiovascular Magnetic Resonance
Subjects
Nuclear Medicine & Medical Imaging
1102 Cardiovascular Medicine And Haematology
Publication Status
Published
Start Date
2016-01-27
Finish Date
2016-01-30
Coverage Spatial
Los Angeles, CA