GeneXpert-A Game-Changer for Tuberculosis Control?
File(s)
Published version
Author(s)
Evans, CA
Type
Journal Article
Abstract
Tuberculosis (TB) kills more people
than any other single infection, the global
burden of TB cases and drug resistance
are increasing [1], and most patients still
only have access to an inadequate diagnostic
test developed more than a century
ago. Recent evaluations of a desktop
machine called the GeneXpert MTB/
RIF that in less than two hours simultaneously
detects Mycobacterium tuberculosis
and tests for drug resistance have stimulated
tremendous enthusiasm [2,3]. Is this
the breakthrough that TB control has
been waiting for?
than any other single infection, the global
burden of TB cases and drug resistance
are increasing [1], and most patients still
only have access to an inadequate diagnostic
test developed more than a century
ago. Recent evaluations of a desktop
machine called the GeneXpert MTB/
RIF that in less than two hours simultaneously
detects Mycobacterium tuberculosis
and tests for drug resistance have stimulated
tremendous enthusiasm [2,3]. Is this
the breakthrough that TB control has
been waiting for?
Date Issued
2011-07-26
Date Acceptance
2011-07-26
Citation
PLOS Medicine, 2011, 8 (7)
ISSN
1549-1277
Publisher
Public Library of Science
Journal / Book Title
PLOS Medicine
Volume
8
Issue
7
Copyright Statement
© 2011 Carlton A. Evans. This is an open-access article distributed under the terms of the Creative
Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium,
provided the original author and source are credited.
Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium,
provided the original author and source are credited.
License URL
Subjects
Science & Technology
Life Sciences & Biomedicine
Medicine, General & Internal
General & Internal Medicine
MEDICINE, GENERAL & INTERNAL
MULTIDRUG-RESISTANT TUBERCULOSIS
MYCOBACTERIUM-TUBERCULOSIS
RIFAMPIN RESISTANCE
DRUG-RESISTANCE
DIAGNOSIS
MTB/RIF
TB
COUNTRIES
POVERTY
TRENDS
Publication Status
Published
Article Number
e1001064