Calculating the effect of ribs on the focus quality of a therapeutic spherical random phased array
File(s)Sensors-21-01211 Published paper.pdf (6.13 MB)
Published version
Author(s)
Zubair, Muhammad
Dickinson, Robert
Type
Journal Article
Abstract
The overlaying rib cage is a major hindrance in treating liver tumors with high intensity focused ultrasound (HIFU). The problems caused are overheating of the ribs due to its high ultrasonic absorption capability and degradation of the ultrasound intensity distribution in the target plane. In this work, a correction method based on binarized apodization and geometric ray tracing approach was employed to avoid heating the ribs. A detailed calculation of the intensity distribution in the focus plane was undertaken to quantify and avoid the effect on HIFU beam generated by a 1-MHz 256-element random phased array after the ultrasonic beam passes through the rib cage. Focusing through the ribs was simulated for 18 different idealized ribs-array configurations and 10 anatomically correct ribs-array configurations, to show the effect of width of the ribs, intercostal spacing and the relative position of ribs and array on the quality of focus, and to identify the positions that are more effective for HIFU applications in the presence of ribs. Acoustic simulations showed that for a single focus without beam steering and for the same total acoustic power, the peak intensity at the target varies from a minimum of 211 W/cm2 to a maximum of 293 W/cm2 for a nominal acoustic input power of 15 W, whereas the side lobe level varies from 0.07 Ipeak to 0.28 Ipeak and the separation between the main lobe and side lobes varies from 2.5 mm to 6.3 mm, depending on the relative positioning of the array and ribs and the beam alignment. An increase in the side lobe level was observed by increasing the distance between the array and the ribs. The parameters of focus splitting and the deterioration of focus quality caused by the ultrasonic propagation through the ribs were quantified in various possible different clinical scenarios. In addition to idealized rib topology, anatomical realistic ribs were used to determine the focus quality of the HIFU beam when the beam is steered both in axial and transverse directions and when the transducer is positioned at different depths from the rib cage.
Date Issued
2021-02-09
Date Acceptance
2021-02-04
Citation
Sensors, 2021, 21 (4)
ISSN
1424-8220
Publisher
MDPI AG
Journal / Book Title
Sensors
Volume
21
Issue
4
Copyright Statement
© 2021 by the authors.Licensee MDPI, Basel, Switzerland.This article is an open access articledistributed under the terms andconditions of the Creative CommonsAttribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/)
License URL
Subjects
Science & Technology
Physical Sciences
Technology
Chemistry, Analytical
Engineering, Electrical & Electronic
Instruments & Instrumentation
Chemistry
Engineering
random phased array
transcostal
therapy
HIFU
rib cage
ultrasound intensity
focus quality
HIFU
focus quality
random phased array
rib cage
therapy
transcostal
ultrasound intensity
Acoustics
High-Intensity Focused Ultrasound Ablation
Humans
Ribs
Transducers
Ultrasonography
Ribs
Humans
Ultrasonography
Transducers
Acoustics
High-Intensity Focused Ultrasound Ablation
0301 Analytical Chemistry
0805 Distributed Computing
0906 Electrical and Electronic Engineering
0502 Environmental Science and Management
0602 Ecology
Analytical Chemistry
Publication Status
Published
Article Number
ARTN 1211