Risk of Anaphylaxis on commercial flights
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Published version
Author(s)
Turner, Paul
Type
Journal Article
Abstract
Purpose of Review:
Air travel has now returned to pre-pandemic levels, with over 10.5 billion passengers in 2024. Many of these passengers have food allergies, and there is a perception that allergic reactions are common during commercial flights.
Recent findings:
A recent systematic review and meta-analysis reported an incidence of in-flight medical events due to allergic reactions of 0.7 (95%CI 0.4–1.1) events per million passengers. For those with food allergies, the incidence of allergic reactions is around 10-100 times lower than that reported for
reactions “on the ground” – equivalent to 1 reaction per 3600 food-allergic passengers in any one year period. Reassuringly, there is no evidence that this rate had increased over the past 30 years, despite significant increases in both the prevalence of food allergy and passenger numbers.
Summary:
Allergic reactions during commercial flights are uncommon, however this is very likely to be confounded by the many precautions food-allergic passengers and their families take when flying. Nonetheless, the data confirm that flying can be safe for those with food allergies. While air travel
continues to present numerous challenges to those with food allergy, this can be mitigated by consistent and helpful airline policies which address the concerns of food-allergic individuals.
Air travel has now returned to pre-pandemic levels, with over 10.5 billion passengers in 2024. Many of these passengers have food allergies, and there is a perception that allergic reactions are common during commercial flights.
Recent findings:
A recent systematic review and meta-analysis reported an incidence of in-flight medical events due to allergic reactions of 0.7 (95%CI 0.4–1.1) events per million passengers. For those with food allergies, the incidence of allergic reactions is around 10-100 times lower than that reported for
reactions “on the ground” – equivalent to 1 reaction per 3600 food-allergic passengers in any one year period. Reassuringly, there is no evidence that this rate had increased over the past 30 years, despite significant increases in both the prevalence of food allergy and passenger numbers.
Summary:
Allergic reactions during commercial flights are uncommon, however this is very likely to be confounded by the many precautions food-allergic passengers and their families take when flying. Nonetheless, the data confirm that flying can be safe for those with food allergies. While air travel
continues to present numerous challenges to those with food allergy, this can be mitigated by consistent and helpful airline policies which address the concerns of food-allergic individuals.
Date Issued
2025-10-01
Date Acceptance
2025-07-01
Citation
Current Opinion in Allergy and Clinical Immunology, 2025, 25 (5), pp.336-342
ISSN
1473-6322
Publisher
Lippincott, Williams & Wilkins
Start Page
336
End Page
342
Journal / Book Title
Current Opinion in Allergy and Clinical Immunology
Volume
25
Issue
5
Copyright Statement
© 2025 The Author(s). Published by Wolters Kluwer Health, Inc. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distri- bution, and reproduction in any medium, provided the original work is properly cited.
License URL
Identifier
10.1097/ACI.0000000000001090
Subjects
allergic reaction
anaphylaxis
epinephrine
food
in-flight medical event
Publication Status
Published
Date Publish Online
2025-07-14