The interfacial heat transfer coefficient (IHTC) for titanium alloys is an important parameter in non-isothermal hot stamping processes to determine the temperature field as well as temperature-dependent material behaviours that consequently affect the post-form properties of the formed components. However, the IHTC for titanium alloys in hot stamping processes has seldom been studied before. In the present research, the effects of contact pressure, lubricant, surface roughness, tooling material and initial blank temperature on the IHTC for the titanium alloy Ti-6Al-4V were studied and modelled to characterise the IHTC values under various hot stamping conditions as well as identify the functional mechanisms affecting the IHTC. Furthermore, the results of hot stamping of Ti-6Al4V wing stiffener components were used to verify the simulation results of the temperature field of the formed component with an error of less than 5%.