LC-MS/MS confirms that COX-1 drives vascular prostacyclin whilst gene expression pattern reveals non-vascular sites of COX-2 expression

Kirkby, NS; Zaiss, AK; Urquhart, P; Jiao, J; Austin, PJ; Al-Yamani, M; Lundberg, MH; MacKenzie, LS; Warner, TD; Nicolaou, A; Herschman, HR; Mitchell, JA

doi:https://www.dx.doi.org/10.1371/journal.pone.0069524

File(s)

LC-MS/MS confirms that COX-1 drives vascular prostacyclin whilst gene expression pattern reveals non-vascular sites of COX-2 expression..pdf (777.61 KB)

Published version

Author(s)

Kirkby, NS

Zaiss, AK

Urquhart, P

Jiao, J

Austin, PJ

more

Type

Journal Article

Date Issued

2013-07-09

Date Acceptance

2013-06-07

Citation

PLoS ONE, 2013, 8 (7)

URI

http://hdl.handle.net/10044/1/22001

DOI

https://www.dx.doi.org/10.1371/journal.pone.0069524

ISSN

1932-6203

Publisher

Public Library of Science

Journal / Book Title

PLoS ONE

Volume

8

Issue

7

Copyright Statement

© 2013 Kirkby et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

License URL

Attribution 4.0 International

Identifier

ARTN e69524

Subjects

Science & Technology

Multidisciplinary Sciences

Science & Technology - Other Topics

MULTIDISCIPLINARY SCIENCES

NONSTEROIDAL ANTIINFLAMMATORY DRUGS

GASTROINTESTINAL TOXICITY

SYNTHASE CYCLOOXYGENASE

PROSTAGLANDIN SYNTHASE

CARDIOVASCULAR-SYSTEM

MESSENGER-RNA

INHIBITION

DISRUPTION

MICE

INFLAMMATION

Publication Status

Published

Article Number

ARTN e69524