Angiotensin II type-1 receptor antibody in solid organ transplantation - is it time to test?
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Published version
Author(s)
Martin, Paul James Patrick
Willicombe, Michelle
Roufosse, Candice
Type
Journal Article
Abstract
Angiotensin II type-1 receptor antibody (AT1R-Ab) has been mooted as a potential effector of both acute and chronic antibody mediated rejection (AMR). A growing body of literature on the topic is now coming under scrutiny in the context of the evolving Banff AMR diagnostic classification system and refinement of recommendations for histocompatibility testing by the Sensitization in Transplantation Assessment of Risk (STAR) workgroup. This mini-review discusses the latest understanding of pathophysiological mechanisms, clinical evidence for the pathogenicity of AT1R-Ab, and methods of laboratory testing.
Date Issued
2024-11-13
Date Acceptance
2024-10-15
Citation
Transplant International, 2024, 37
ISSN
0934-0874
Publisher
Frontiers Media S.A.
Journal / Book Title
Transplant International
Volume
37
Copyright Statement
Copyright © 2024 Martin, Willicombe and Roufosse. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
License URL
Identifier
https://www.frontierspartnerships.org/journals/transplant-international/articles/10.3389/ti.2024.13280/full
Publication Status
Published
Article Number
13280
Date Publish Online
2024-11-13