Thermally drawn polymeric catheters for MR-guided cardiovascular intervention
Author(s)
Type
Journal Article
Abstract
Cardiovascular diseases (CVDs), including congenital heart diseases (CHD), present significant global health challenges, emphasizing the need for safe and effective treatment modalities. Fluoroscopy-guided endovascular interventions are widely utilized but raise concerns about ionizing radiation, especially in pediatric cases. Magnetic resonance imaging (MRI) offers a radiation-free alternative with superior soft tissue visualization and functional insights. However, the lack of compatible instruments remains a major obstacle. An adapted thermal drawing platform that enables low-cost and rapid prototyping of instruments for MR-guided endovascular interventions is introduced. This platform is demonstrated through the development of two exemplary catheter systems: a tendon-driven steerable catheter with helical lumina and an active tracking Tiger-shaped catheter with an embedded coaxial wire. These catheters exhibit mechanical properties comparable to commercial counterparts and show promising outcomes in both in vitro and in vivo feasibility testing. This scalable thermal drawing platform addresses the limitations of existing manufacturing approaches and facilitates the exploration of diverse designs, potentially accelerating advancements in catheter technologies for MR-guided cardiovascular interventions.
Date Issued
2024-12
Date Acceptance
2024-10-01
Citation
Advanced Science, 2024, 11 (45)
ISSN
2198-3844
Publisher
Wiley
Journal / Book Title
Advanced Science
Volume
11
Issue
45
Copyright Statement
© 2024 The Author(s). Advanced Science published by Wiley-VCH GmbH
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
License URL
Identifier
https://onlinelibrary.wiley.com/doi/10.1002/advs.202407704
Subjects
ADULTS
ARTERIES
cardiovascular interventions
catheter
Chemistry
Chemistry, Multidisciplinary
CURVATURE
DESIGN
endovascular interventions
MAGNETIC-RESONANCE
Materials Science
Materials Science, Multidisciplinary
MRI
Nanoscience & Nanotechnology
Physical Sciences
Science & Technology
Science & Technology - Other Topics
Technology
thermal drawings
TRACKING
Publication Status
Published
Article Number
2407704
Date Publish Online
2024-10-15