Non-invasive coronary wave intensity analysis
File(s)
Published version
Author(s)
Broyd, CJ
Rigo, F
Davies, J
Type
Journal Article
Abstract
Wave intensity analysis is calculated from
simultaneously acquired measures of pressure and flow.
Its mathematical computation produces a profile that provides
quantitative information on the energy exchange driving
blood flow acceleration and deceleration. Within the
coronary circulation it has proven most useful in describing
the wave that originates from the myocardium and that
is responsible for driving the majority of coronary flow,
labelled the backward decompression wave. Whilst this
wave has demonstrated valuable insights into the pathogenic
processes of a number of disease states, its measurement
is hampered by its invasive necessity. However, recent
work has used transthoracic echocardiography and an
established measures of central aortic pressure to produce
coronary flow velocity and pressure waveforms respectively.
This has allowed a non-invasive measure of coronary
wave intensity analysis, and in particular the backward
decompression wave, to be calculated. It is anticipated that
this will allow this tool to become more applicable and
widespread, ultimately moving it from the research to the
clinical domain
simultaneously acquired measures of pressure and flow.
Its mathematical computation produces a profile that provides
quantitative information on the energy exchange driving
blood flow acceleration and deceleration. Within the
coronary circulation it has proven most useful in describing
the wave that originates from the myocardium and that
is responsible for driving the majority of coronary flow,
labelled the backward decompression wave. Whilst this
wave has demonstrated valuable insights into the pathogenic
processes of a number of disease states, its measurement
is hampered by its invasive necessity. However, recent
work has used transthoracic echocardiography and an
established measures of central aortic pressure to produce
coronary flow velocity and pressure waveforms respectively.
This has allowed a non-invasive measure of coronary
wave intensity analysis, and in particular the backward
decompression wave, to be calculated. It is anticipated that
this will allow this tool to become more applicable and
widespread, ultimately moving it from the research to the
clinical domain
Date Issued
2017-06-19
Date Acceptance
2017-03-16
Citation
International Journal of Cardiovascular Imaging, 2017, 33 (7), pp.1061-1068
ISSN
1569-5794
Publisher
Springer Verlag
Start Page
1061
End Page
1068
Journal / Book Title
International Journal of Cardiovascular Imaging
Volume
33
Issue
7
Copyright Statement
© The Author(s) 2017. This article is an open access publication
License URL
Subjects
Science & Technology
Life Sciences & Biomedicine
Cardiac & Cardiovascular Systems
Radiology, Nuclear Medicine & Medical Imaging
Cardiovascular System & Cardiology
Coronary physiology
Wave intensity analysis
Microcirculation
AORTIC-VALVE-REPLACEMENT
FLOW-RESERVE
DOPPLER-ECHOCARDIOGRAPHY
SUCTION WAVE
ARTERY
CARDIOMYOPATHY
DYNAMICS
VELOCITY
STENOSIS
Publication Status
Published