Research in progress-LungSEARCH: a randomised controlled trial of surveillance for the early detection of lung cancer in a high-risk group
File(s)
Published version
Author(s)
Type
Journal Article
Abstract
Low-dose CT screening for lung cancer is effective but expensive. Therefore, cheaper or more focused screening strategies may be required. LungSEARCH is a randomised prospective trial of 1568 high-risk individuals (ie, current or former moderate to heavy smokers with mild/moderate COPD) who undergo either annual sputum cytology/cytometry testing or no screening. Those with abnormal sputum then receive annual CT and fluorescent bronchoscopy for the remainder of 5 years, to identify early stage lung cancer. It is hoped that these simple initial tests could identify those requiring expensive CT scans, and the aim is to demonstrate a stage shift towards early stage cancers.
Date Issued
2015-07-02
Date Acceptance
2015-06-17
Citation
Thorax, 2015, 71 (1), pp.91-93
ISSN
0040-6376
Publisher
BMJ Publishing Group
Start Page
91
End Page
93
Journal / Book Title
Thorax
Volume
71
Issue
1
Copyright Statement
This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/
License URL
Subjects
Respiratory System
1103 Clinical Sciences
Publication Status
Published