Injection-moulded short-fibre composites are lightweight materials suitable for highvolume applications; however, current simulation methods for these materials cannot yet predict failure accurately. This work proposes a methodology to predict failure of injection-moulded short-glass-fibre reinforced PA66 composite components, based on experimentally measured properties. The material's fracture toughness was characterized for different fibre orientations, and these values were used as the input for cohesive zone modelling in Finite Element analyses of the components, coupled with simulations of the injection-moulding process. The coupled process/structural simulations using cohesive zone modelling presented excellent agreement with the experimental data of the component tests, highlighting the importance of accounting for the finite fracture toughness of the material to accurately predict the ultimate failure of injection-moulded short-fibre reinforced PA66 composite components.