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Studies towards the biomimetic synthesis of resorcylic acid lactones
File(s)
Author(s)
Cookson, Rosa Ellen
Type
Thesis
Abstract
Resorcylic acid lactones (RALs) are a biologically important and structurally interesting class of natural products. Recently the Barrett group has developed a novel, biomimetic strategy to access RALs that bypasses many common inefficiencies inherent to more classical synthetic approaches. The focus of this thesis consists of a synthetic study of the RALs radicicol and paecilomycin B that utilised this methodology.
Version
Open Access
Date Issued
2015-09
Date Awarded
2015-11
URI
DOI
Copyright Statement
Attribution NoDerivatives 4.0 International Licence (CC BY-ND)
License URL
Advisor
Barrett, Anthony
Sponsor
Engineering and Physical Sciences Research Council
Publisher Department
Chemistry
Publisher Institution
Imperial College London
Qualification Level
Doctoral
Qualification Name
Doctor of Philosophy (PhD)