Pediatric asthma comorbidities: global impact and unmet needs
File(s)
Published version
Author(s)
Type
Journal Article
Abstract
Real-world data on the range and impact of comorbid health conditions that affect pediatric asthma are scant, especially from developing countries. Lack of data hinders effective diagnosis, treatment, and overall management of these complex cases. We, hereby, describe the common pediatric asthma comorbid conditions in terms of evidence for association, potential mechanisms of impact on asthma control, and treatment benefit. Obesity, upper airway allergies, dysfunctional breathing, multiple sensitizations, depressive disorders, food allergy, and gastro-esophageal reflux are common associations with difficult-to-treat asthma. On the other hand, asthma symptoms and/or management may negatively impact the well-being of children through drug adverse effects, worsening of anaphylaxis symptoms, and disturbing mental health.
Awareness of these ailments may be crucial for designing the optimum care for each asthmatic child individually and may ultimately improve the quality of life of patients and their families. A multidisciplinary team of physicians is required to identify and manage such comorbidities aiming to mitigate the over-use of asthma pharmacotherapy. Asthma research should target relevant real-world difficulties encountered at clinical practice and focus on interventions that would mitigate the impact of such comorbidities. Finally, policymakers and global healthcare organizations are urged to recognize pediatric asthma control as a healthcare priority and allocate resources for research and clinical interventions. In other words, global asthma control needs support by compassionate scientific partnership.
Awareness of these ailments may be crucial for designing the optimum care for each asthmatic child individually and may ultimately improve the quality of life of patients and their families. A multidisciplinary team of physicians is required to identify and manage such comorbidities aiming to mitigate the over-use of asthma pharmacotherapy. Asthma research should target relevant real-world difficulties encountered at clinical practice and focus on interventions that would mitigate the impact of such comorbidities. Finally, policymakers and global healthcare organizations are urged to recognize pediatric asthma control as a healthcare priority and allocate resources for research and clinical interventions. In other words, global asthma control needs support by compassionate scientific partnership.
Date Issued
2024-05-01
Date Acceptance
2024-04-18
Citation
The World Allergy Organization Journal, 2024, 17 (5)
ISSN
1939-4551
Publisher
Elsevier
Journal / Book Title
The World Allergy Organization Journal
Volume
17
Issue
5
Copyright Statement
© 2024 The Authors. Published by Elsevier Inc. on behalf of World Allergy Organization. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Identifier
10.1016/j.waojou.2024.100909
Subjects
ALLERGIC RHINITIS
Allergy
ASSOCIATION
Asthma
Asthma control
ATOPIC-DERMATITIS
Children
CHILDREN
CLINICAL IMPACT
Comorbid conditions
DISEASE
ENVIRONMENTAL INTERVENTION
FOOD ALLERGY
GASTROESOPHAGEAL-REFLUX
Immunology
Life Sciences & Biomedicine
LUNG-FUNCTION
Obesity
Science & Technology
Upper airway
Publication Status
Published
Article Number
100909
Date Publish Online
2024-05-22