Microbiota and faecal microbiota transplant
File(s)
Accepted version
Author(s)
Mullish, Benjamin H
Alexander, James L
Segal, Jonathan P
Type
Journal Article
Abstract
As the range of disease states associated with the gut microbiome expands - and the mechanistic links between the gut microbiome and host physiology further deepens – so interest also grows in microbiome manipulation as medical therapy. In particular, bolstered by its established role in recurrent C. difficile infection (and promising results in other conditions), faecal microbiota transplant (FMT) has remained of growing global focus. This article reviews the key FMT-based studies published between April 2020 - March 2021. While the COVID-19 pandemic was the dominant challenge of the year, important FMT trials of interest were published for patients with a range of different conditions. The emergence of ‘next generation’ microbiome therapeutics offers an additional perspective and new opportunities within the field.
Date Acceptance
2021-04-08
Citation
Microbiota in Health and Disease, 3
ISSN
2704-8845
Publisher
European Helicobacter and Microbiota Study Group
Journal / Book Title
Microbiota in Health and Disease
Volume
3
Copyright Statement
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Sponsor
Imperial College Healthcare NHS Trust- BRC Funding
Identifier
https://www.microbiotajournal.com/article/586
Grant Number
RDA02
Publication Status
Published