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  5. A compact targeted drug delivery mechanism for a next generation wireless capsule endoscope
 
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A compact targeted drug delivery mechanism for a next generation wireless capsule endoscope
File(s)
art%3A10.1007%2Fs12213-016-0088-9.pdf (1.86 MB)
Published version
OA Location
http://link.springer.com/article/10.1007/s12213-016-0088-9
Author(s)
Woods, S
Constandinou, TG
Type
Journal Article
Abstract
This paper reports a novel medication release and delivery mechanism as part of a next generation wireless capsule endoscope (WCE) for targeted drug delivery. This subsystem occupies a volume of only 17.9mm3 for the purpose of delivering a 1 ml payload to a target site of interest in the small intestinal tract. An in-depth analysis of the method employed to release and deliver the medication is described and a series of experiments is presented which validates the drug delivery system. The results show that a variable pitch conical compression spring manufactured from stainless steel can deliver 0.59 N when it is fully compressed and that this would be sufficient force to deliver the onboard medication.
Date Issued
2016-05-13
Date Acceptance
2016-04-23
Citation
Journal of Micro-Bio Robotics, 2016, 11 (1), pp.19-34
URI
http://hdl.handle.net/10044/1/32880
DOI
https://www.dx.doi.org/10.1007/s12213-016-0088-9
ISSN
2194-6426
Publisher
Springer
Start Page
19
End Page
34
Journal / Book Title
Journal of Micro-Bio Robotics
Volume
11
Issue
1
Copyright Statement
© The Author(s) 2016. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
License URL
http://creativecommons.org/licenses/by/4.0/
Publication Status
Published
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