The pregnancy microbiome and preterm birth
File(s)Bayar2020_Article_ThePregnancyMicrobiomeAndPrete (1).pdf (376.99 KB)
Published version
Author(s)
Bayar, Erna
Bennett, Phillip R
Chan, Denise
Sykes, Lynne
MacIntyre, David
Type
Journal Article
Abstract
Preterm birth is a global health concern and continues to contribute to substantial neonatal morbidity and mortality despite advances in obstetric and neonatal care. The underlying aetiology is multi-factorial and remains incompletely understood. In this review, the complex interplay between the vaginal microbiome in pregnancy and its association with preterm birth is discussed in depth. Advances in the study of bacteriology and an improved understanding of the human microbiome have seen an improved awareness of the vaginal microbiota in both health and in disease.
Date Issued
2020-08-14
Date Acceptance
2020-07-30
Citation
Springer Seminars in Immunopathology, 2020, 42, pp.487-499
ISSN
1863-2297
Publisher
Springer Verlag
Start Page
487
End Page
499
Journal / Book Title
Springer Seminars in Immunopathology
Volume
42
Copyright Statement
© The Author(s) 2020. This article is licensed under a Creative Commons
Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as
you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were
made. The images or other third party material in this article are included
in the article's Creative Commons licence, unless indicated otherwise in a
credit line to the material. If material is not included in the article's
Creative Commons licence and your intended use is not permitted by
statutory regulation or exceeds the permitted use, you will need to obtain
permission directly from the copyright holder. To view a
Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as
you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were
made. The images or other third party material in this article are included
in the article's Creative Commons licence, unless indicated otherwise in a
credit line to the material. If material is not included in the article's
Creative Commons licence and your intended use is not permitted by
statutory regulation or exceeds the permitted use, you will need to obtain
permission directly from the copyright holder. To view a
License URL
Sponsor
Imperial College Healthcare NHS Trust- BRC Funding
March of Dimes
Identifier
https://link.springer.com/article/10.1007%2Fs00281-020-00817-w
Grant Number
RDD03 79560
22-FY18-821
Subjects
Science & Technology
Life Sciences & Biomedicine
Immunology
Pathology
Preterm birth
Pregnancy
Vaginal microbiome
Lactobacillus
CERVICAL INTRAEPITHELIAL NEOPLASIA
BACTERIAL VAGINOSIS
VAGINAL MICROBIOME
INTRAAMNIOTIC INFECTION
CERVICOVAGINAL MICROBIOTA
CLINICAL-SIGNIFICANCE
PREMATURE RUPTURE
GUT MICROBIOTA
ORAL BACTERIA
RISK
Lactobacillus
Pregnancy
Preterm birth
Vaginal microbiome
Immunology
1103 Clinical Sciences
Publication Status
Published
Date Publish Online
2020-08-14