Trp-ing upon new repressors
File(s)Final_Broedel_Nat Chem Biol.docx (752.28 KB)
Accepted version
Author(s)
Broedel, AK
Isalan, Mark
Type
Journal Article
Abstract
Bioengineers have used directed evolution to generate a new family of synthetic transcription factors based on the tryptophan repressor. The evolved repressor family enables researchers to build new gene circuits for biomedical applications.
Date Issued
2018-02-26
Date Acceptance
2018-02-02
Citation
Nature Chemical Biology, 2018, 14, pp.328-329
ISSN
1552-4450
Publisher
Nature Publishing Group
Start Page
328
End Page
329
Journal / Book Title
Nature Chemical Biology
Volume
14
Copyright Statement
© 2018 Nature America Inc., part of Springer Nature. All rights reserved.
Sponsor
Commission of the European Communities
Wellcome Trust
Wellcome Trust
Biotechnology and Biological Sciences Research Council (BBSRC)
Grant Number
610730
102944/Z/13/Z
102944/Z/13/Z
BB/P020615/1
Subjects
Science & Technology
Life Sciences & Biomedicine
Biochemistry & Molecular Biology
REPLICATION
0304 Medicinal And Biomolecular Chemistry
0601 Biochemistry And Cell Biology
Publication Status
Published